The Incidence Rate of Neonatal Deaths/Abortion in Pregnant Females Infected with Toxoplasma Gondii in District Torghar: A Retrospective Study

Abstract

Toxoplasma gondii, a parasite that consists of only one cell, is the agent that causes toxoplasmosis, often known as the toxoplasmosis infection. The retrospective study was conducted on 350 pregnant females at different Basic Health Units of the District Torghar from July 2020 to August 2022. Toxoplasma gondii screening using Toxoplasma IgG/IgM cassettes (LINEAR) and Rapid Labs' Toxoplasmosis Latex Test Kit. We added data from 350 positive pregnant females such as the first trimester 152, 43.3%, second trimester 113, 32.2%, and third trimester 85, 24.2%. The mean of neonatal deaths/abortion in pregnant females was calculated as 116.6, SD 27.47 and Variance, σ2 was observed as 754.88 against 95%, 1.960σx̄, 116.6667 ±31.091 (±26.65%). The mean of affected age groups with Toxoplasmosis was calculated as 87.5, SD 19.65 and Variance, σ2 was observed as 386.25 against 95%, 1.960σx̄, 87.5 ±19.26 (±22.01%). The mean of Positive cases of Toxoplasmosis reported by BHUs was calculated as 70, SD 36.98 and Variance, σ2 was observed as 1368 against 95%, 1.960σx̄, 70 ±32.42 (±46.31%). The mean of Neonatal deaths/abortion by Toxoplasmosis was calculated as 58.33, SD 54.7 and Variance, σ2 was observed as 2998.55 against 95%, 1.960σx̄, 58.3333 ±43.816 (±75.11%). The mean of Neonatal deformities caused by Toxoplasmosis was calculated as 8.2, SD 3.70 and Variance, σ2 was observed as 13.76 against 95%, 1.960σx̄, 116.6667 ±130.256 (±111.65%). The n=350 patients tested positive for IgG 46 (13.1%), IgM 279 (79.7%), and IgG/IgM 25 (7.1%). The mean of Toxoplasmosis antibodies (IgG, IgM, IgG/IgM) was calculated as 116.6, SD 115.1 and Variance, σ2 was observed as 13249.5 against 95%, 1.960σx̄, 8.2 ±3.251 (±39.65%). The mean of Lifestyle/nature of patients was calculated as 72, SD 23.2 and Variance, σ2 was observed as 542 against 95%, 1.960σx̄, 72 ±26.345 (±36.59%). Our study findings suggested that Lack of health facilities, lack of knowledge of Toxoplasmosis transmission, infection and prevention, medical education, and awareness is contributing pillar of the infection and neonatal deaths.