Frequency of Abnormal Brain Imaging Findings in Patients with Idiopathic Generalized Epilepsy Presenting to Neurology Unit of a Tertiary Care Hospital Leh Peshawar
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Abstract
Background: Epilepsy, as defined by the International League against Epilepsy, is a syndrome characterized by at least two unprovoked seizures that affect over 70 million individuals worldwide. Although epilepsy is predominantly a clinical and EEG-based diagnosis, neuroimaging, particularly MRI, has become an important aspect of the work-up for an epilepsy diagnosis.
Objective: The goal of this study was to determine the frequency of abnormal MRI brain imaging in epileptic patients who came to the Lady Reading Hospital's neurology unit.
Study Design: Lady Reading Hospital Peshawar's Neurology Department conducted a cross-sectional study
Duration of Study: This study was conducted from January 1, 2021, through June 30, 2021.
Methodology: The study included 281 patients, both male and female, who were diagnosed with epilepsy. The International League Against Epilepsy's recommendations is as follows. An MRI was performed in a 2.0 T scanner before the epilepsy protocol was recognized. Images were examined, and some abnormalities were discovered. An MRI of the two patients' brains was performed and reported by a radiologist to look for any abnormal brain lesions. Age, seizure onset age, sub-syndrome, EEG findings, and seizure control were all evaluated in these groups.
Results: MRI findings were abnormal in 81 percent of patients. The participants in this study ranged in age from 16 to 80 years old, with a mean age of 35.793.1051 years, a mean epilepsy duration of 15.156.86 years, and a mean age at diagnosis of 20.637.35 years. In 16.4 percent of patients, abnormal neuroimaging was discovered. Space-occupying lesions accounted for 21.7% of abnormal neuroimaging, tumors 47.9%, cysts 21.7%, and hemorrhages 8.7%. Tables 01 to 07 will explain.
Conclusion: According to the findings of our study, up to a fourth of epileptic patients who had an MRI had abnormal findings.