Isolation and Identification of MDR Solmonella Typhi from Different Food Products in District Peshawar, KPK, Pakistan

Abstract

Salmonella enteric typhi is a fatal human pathogen that causes typhoid fever. The most common source of the infection is drinking water. In the present study, 100 samples from different sources (water, chicken, meat, milk, and fruits) were screened for S. typhi, and 68 samples were found positive. Gram staining and different biochemical tests were carried out to identify strains of S. typhi. These isolates were further tested for antibiotic resistance using the disc diffusion method. The prevalence of S. typhi was 100% in chicken meat samples, 76% in milk samples, 24% in drinking water samples, and 72% in fruits and vegetable samples. Among the isolated strains of S. typhi, 39.7% showed resistance to Chloramphenicol, 29.41% to Ciprofloxacin, 100% to Amoxicillin, 0% to Imipenem, 100% to Cefotaxime, 85.29% to Streptomycin, 100% to Erythromycin, 95.58% to Doxycycline, 100% to Rifampicin and 0% resistance to Meropenem. Based on our findings, Imipenem (87% susceptibility) and Meropenem (78% susceptibility) were the most effective antibiotics against various strains of S. typhi.