The Efficacy of Different Derivatives of Viscosupple-mentation use in Patients with Knee Osteoarthritis

Main Article Content

Özkan Yükselmiş

Abstract

Objective: The aim of this study is to examine the effects of vis-co-supplementation with two different agents on pain and functionality in patients with knee osteoarthritis with surgical indication at stage 4 according to Kellgren-Lawrence radiological staging and who do not accept surgery.


Design: Within the scope of the study, 68 patients were studied. According to Kellgren-Lawrence radiological staging criteria, patients were selected from among patients who had surgery at stage 4 but were not accepted for surgery.


Setting: The patients were divided into 2 groups with similar gender and age characteristics. For 34 patients in the first group, 16 mg/2 ml Hylan-GF 20 was applied 3 times to both knees with a one-week inter-val, while the same application was applied with 15 mg/2 ml sodium hy-aluronate to 34 patients in the second group. Case assessments of patients before and 24 weeks after treatment were made in the context of the Lysholm knee scale.


Result: The use of hyaluronic acid and its derivatives for viscosupplementation is preferred for symptomatic treatment in the 2nd and 3rd stages of knee osteoarthritis.


Conclusion: It has been shown that more than 5 injections do not affect the results, and 3-5 injections will be sufficient for the intended therapeutic effect.

Article Details

Section
Articles