Application of fine nursing in the drug resistance of Klebsiella pneumoniae and its influence on immune function

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Ying xi, Lu Yang

Abstract

Objective To explore the application of meticulous nursing in the drug resistance of Klebsiella pneumoniae (KPN) in children and its effect on immune function. Methods 100 children with KPN infection in our hospital from January 2020 to January 2021 were selected and randomly divided into the control group (50 cases) and the observation group (50 cases). The control group was given routine nursing, while the observation group was given fine nursing on the basis of the control group for 2 weeks. The clinical efficacy, KPN resistance, CD4 +, CD8 +, CD4 + / CD8 +, IgA, IgG, IgM levels and satisfaction were compared between the two groups. Results Compared with the control group (72.00%), the total clinical effective rate of the observation group (90.00%) was significantly increased, the difference was statistically significant (P < 0.05). The drug resistance of the observation group to a variety of antimicrobial agents was significantly higher than that of the control group, the difference was statistically significant (P < 0.05). Compared with before nursing, CD4 +, CD4 + / CD8 + were significantly increased, CD8 +, IgA, IgG, IgM were significantly decreased, the difference was statistically significant (P < 0.05). Compared with the control group (76.00%), the nursing satisfaction of the observation group was significantly higher (P < 0.05). Conclusion Fine nursing not only has a good application effect in children with KPN resistance, but also can significantly improve the immune function of children, which is worthy of clinical reference.

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