Research and Nursing Experience of Recombinant Human Epidermal Growth Factor Gel Promoting Oral Mucosal Erosion Lesion Healing

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Bo Yu, Bing Xu, Chonggui Qiu, Yang Liu

Abstract

Erosion is a primary clinical manifestation of oral mucosal lesions. Contact between food and the mucosal surface during chewing can easily cause oral mucosal infection and adversely affect the daily lives of patients. Conventional clinical treatment cannot overcome the problems of oral mucosal erosion. This study aimed to analyze the application effect of recombinant human epidermal growth factor (rhEGF) gel on oral mucosal erosion lesions. The subjects of this study were 120 patients with oral mucosal erosion lesions, who were divided, according to random number table method, into a contrast group and rhEGF group with 60 cases in each. The patients in the contrast group were treated with ethacridine lactate, and the rhEGF group patients were treated with rhEGF gel. Patients in both groups received corresponding nursing measures. Compared with the contrast group, the rhEGF group had a lower visual analog scale score, Reticulation/keratosis, erythema, and ulceration score, and inflammatory cytokine levels, as well as a higher total effective rate and faster patient recovery, indicating that the rhEGF gel had significant efficacy and is worthy of promotion.

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