Insight view of Bronchial Asthma: Phenotypes, Classification and Management in Children

Abstract

Asthma remains a global public health problem and is a common chronic respiratory disease. It is characterized by airway inflammation related to variable airflow obstruction, airway hyper-responsiveness, and airway wall remodeling. Smoking, obesity and age are an important risk factor for asthma morbidity. During the last decades bronchial asthma has become the most common disease of childhood. Accordingly, many epidemiological and genetic studies have dealt with its origin.  Clinically important patient subgroups can be found via phenotypic clustering, which has implications for the development of specialized therapy approaches and clinical trial designs. Shared goals for asthma management can be achieved in various ways, taking into account different healthcare systems, medication availability, and cultural and personal preferences. The aim of the current study to review the phenotypes of bronchial asthma, classfication and different modalities of management.