Contribution to a study of variations in biochemical parameters in COVID-19 patients in the province of Saida.

Abstract

Since December 2019, Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), emerged in Wuhan and subsequently became a pandemic. Algeria has been severely affected by the virus. COVID-19 affects people in different ways.

The objective of our study is to investigate the direct and indirect complications caused by COVID-19 virus in confirmed patients. The various experimental stages of this project were conducted at Dr. Chouikhi Medical Laboratory in Saida from June 2020 to December 2021, with a total of 1538 patients. This study aims to identify and evaluate the complications of the COVID-19 epidemic in affected individuals and their impact on their health.

Based on clinical and biological data collected from medical records of COVID-19 patients, our results show that this disease exhibits variations in levels of Troponin (<10 ng/ml), CRP (<6), and particularly in D-dimers, which were observed to be higher (greater than 500 ng/ml (<500)) in severe cases compared to non-severe cases. These variations have an impact on biochemical parameters of the liver, kidneys, and lungs. This allows us to understand the effects of COVID-19 on other organs such as the liver and kidneys.