Staphylococcus aureus Nasal Carriage and Rheumatoid Arthritis Disease

Abstract

Historical research into the involvement of infectious agents in the development of autoimmune disorders (ADs) has been aggressively reassessed in recent years due to the interest in the link between the microbiome and ADs. Similar to the gut, the skin hosts a diverse community of microbes that may modulate both the body's innate and adaptive immune responses. One of the most prominent members of the skin microbiome, S. aureus is able to colonize the anterior nares in healthy people. The literature shows that nasal colonization is much more common in ADs patients than in healthy people, which may have a role in the aetiology and manifestation of the disease. As a result, the present narrative review centred on the ways in which S. aureus is linked to rheumatoid arthritis and the immune system.