Identification and Prevalence rate of Hyponatremia in Patients with Liver Cirrhosis at PIMS Hospital Islamabad Pakistan

Abstract

As we know that Chronic liver disease (CLD) is very common ailment in Pakistan and other world as well. Whenever liver got damaged or abnormal than it does not working properly and cause different nutritional and electrolytes imbalance in body of the patients. Therefore we conducted the current research study to find the variation in sodium level in CLD patients and to identify the frequency rate of hyponatremia in patients of chronic liver disease at Department of Medicine, PIMS Hospital Islamabad from 1^st January 2021 to 30 June. For the current research study we were selected 175 cases of CLD were selected through OPD. Blood sample was obtained and level of sodium was tested and hyponatremia was noted. SPSS v.20 was used to analyses the data. Frequency and percentage was calculated for hyponatremia. The mean age of the patients was 46.31±15.82 years. There were 54% males and 46% females. Mean duration of CLD was 5.76±2.79years. Child-Pugh grade A was noticed in 34%, grade B in 30.7% and grade C in 35.3%. The mean sodium level 142.71±15.54mmol/L. Hyponatremia was present in 33.3% cases. Mild hyponatremia was observed in 35(48%) cases, moderate hyponatremia in 37(50%) and severe hyponatremia in 3(3%) patients. Hyponatremia was present in 25.5% Child-Pugh class A, 39.1% in Child-Pugh class B and 35.8% in Child-Pugh class C. The difference was insignificant (P>0.05). From the Current study we conclude that the Frequency rate of hyponatremia in CLD patients was high.