Study of Association between Elevated Cardiac Markers with Cardiac Arrest

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Mehak Rubab Kazmi et. al.

Abstract

The present study describes the relationship of different cardiac biomarkers with cardiac arrest. Four biomarkers i.e., Troponin, Aspartate aminotransferase, Creatinine Kinase and lactate dehydrogenase were selected. After different tests in experimental group and their comparison with control group, it was found that the value of different biomarkers is significantly higher. Increased value of biomarkers lead to different other diseases in cardiac patients. CK as a cardiac arrest marker gave significant variation when compared to control group. Z score for CK is -12.187. Z score for LDH is -11.819. AST as a cardiac arrest marker gave significant variation when compared to experiment group. Due to increase level of AST in blood there are some diseases that occur in patients. Z score for AST is -12.153. Troponin-I levels were significantly higher in cardiac patients, and can serve as individual diagnostic parameter. P value for Troponin-I was less than 0.05 and Z score for Trop-I is 12.150.

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Author Biography

Mehak Rubab Kazmi et. al.

Mehak Rubab Kazmi1, Shafiq-ur-Rehman1, Sadia Zulfiqar1, Syeda Alikha Ali1, Amina Sajjad1, Amir Mushtaq1, Tooba Noor1, Nadeem-Ullah2, Muhammad Asam Raza3,Anmol Zahra4

  1. Department of Basic and applied Chemistry, University of Central Punjab, Lahore, Pakistan
  2. Department of Biotechnology, University of Central Punjab, Lahore, Pakistan
  3. Department of Chemistry, University of Gujrat, Pakistan
  4. Khawaja Safdar Medical College Sialkot, Pakistan

Corresponding author: mehak.rubab@ucp.edu.pk