An Insight about Polydatin: Mechanism and Health Benefits

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Riham Mohammed Selim Shoeib, Ahmed Omar, Yara Alfakharany

Abstract

       Polydatin is a bioavailable derivative of resveratrol and a powerful stilbenoid polyphenol found naturally. Specifically, polydatin may have biological effects by altering key signalling pathways associated with processes including inflammation, oxidative damage, and apoptosis. Anticancer, cardioprotective, anti-diabetic, gastroprotective, hepatoprotective, neuroprotective, anti-microbial, and health-promoting roles on the renal system, the respiratory system, rheumatoid diseases, skeletal system, and women's health are just some of the suggested essential biological activities for polydatin towards promising therapeutic effects. This assessment of polydatin's health advantages, biological activities, pharmacological mechanisms, and therapeutic targets informs future studies. New information may be gleaned through more clinical trials.

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Author Biography

Riham Mohammed Selim Shoeib, Ahmed Omar, Yara Alfakharany

Riham Mohammed Selim Shoeib, Ahmed Omar, Yara Alfakharany

Clinical Toxicology Department, Faculty of Medicine, Zagazig University, Egypt

Corresponding author: Riham Mohammed Selim Shoeib

E-mail:  reham.selim1911@gmail.com, RMShoaib@medicine.zu.edu.eg