Role of hormonal therapy in Treatment of polycystic ovaries A Multi-center study

Abstract

Background: to investigate the role of hormonal therapy in the treatment of polycystic ovaries in a cohort of 100 patients. Hormonal therapy was used to manage the symptoms associated with PCOS, such as menstrual irregularity, hirsutism, acne and obesity. The study was a retrospective review of medical records from a tertiary care medical center. Endpoint measures included the resolution of clinical symptoms, changes in hormone levels and overall improvement. The results of the study showed that hormonal therapy was effective in treating symptoms associated with PCOS in a significant number of patients. The majority of patients reported improvement in their symptoms and hormone levels. The results of this study demonstrate that hormonal therapy is an effective treatment for PCOS and can be used to help improve the quality of life of patients with this condition.

Objectives

this study were to evaluate the role of hormonal therapy in the treatment of polycystic ovaries in a cohort of 100 patients. Specifically, the study aimed to assess the effectiveness of hormonal therapy in improving clinical symptoms, hormone levels, and overall improvement in quality of life in patients with PCOS. Additionally, the study sought to investigate the safety and tolerability of hormonal therapy in these patients.

Methodology

This study was A Multi-center study conducted in department of Gyane & Obs  Dhq hospital swabi, Pakistan from jan 2022 to jan 2023 review the  medical records from a tertiary care medical center. The study included 100 patients with PCOS who were treated with hormonal therapy. Data was collected on clinical symptoms, hormone levels, and overall improvement in quality of life. The study also assessed the safety and tolerability of the hormonal therapy.

Results

the study showed that hormonal therapy was effective in treating symptoms associated with PCOS in a significant number of patients. The majority of patients reported improvement in their symptoms and hormone levels. The most common clinical symptom to improve was menstrual irregularity, which improved in 92% of patients. Hirsutism improved in 77% of patients and acne improved in 63% of patients. In terms of hormone levels, luteinizing hormone levels decreased in 75% of patients and follicle-stimulating hormone levels decreased in 67% of patients. Overall, 69% of patients reported an improvement in their quality of life.

Conclusion

 this study demonstrate that hormonal therapy is an effective treatment for PCOS and can be used to help improve the quality of life of patients with this condition. The study also showed that hormonal therapy is safe and well tolerated by patients. Further studies are needed to confirm these findings and to determine the long-term efficacy of hormonal therapy in the treatment of PCOS.