Urinary Tract Infection Associated with the Increased Chronic Urothelial Inflammation A Multi-Center Study

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Azra A. Ghani et. al

Abstract

association between chronic urothelial inflammation and urinary tract infections in 100 female patients. Urine samples were analyzed for levels of inflammatory cytokines, and the results were compared to the presence of bacterial pathogens in the urine. It was found that increased levels of inflammatory cytokines were associated with increased risk of urinary tract infections. The results of this study suggest that chronic urothelial inflammation may be a risk factor for UTI in female patients. Further studies are needed to understand the mechanisms by which chronic urothelial inflammation contributes to the development of UTIs.


Objectives


The main objective of this study was to investigate the association between chronic urothelial inflammation and urinary tract infections in 100 female patients.


Methods


This study conducted in department of urology lrh Peshawar from jan 2021 to jan 2022 the study included 100 female patients between the ages of 18 and 65. Urine samples were collected from each patient and analyzed for levels of inflammatory cytokines. The presence of bacterial pathogens in the urine was also determined. The results were then compared to the levels of inflammatory cytokines and the presence of bacterial pathogens.


Results


The results of this study showed that increased levels of inflammatory cytokines were associated with increased risk of urinary tract infections. Specifically, patients with higher levels of inflammatory cytokines were more likely to have a positive urine culture for bacterial pathogens.


Conclusion


This study provides evidence that chronic urothelial inflammation may be a risk factor for UTI in female patients. Further studies are needed to understand the mechanisms by which chronic urothelial inflammation contributes to the development of UTIs.a

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Author Biography

Azra A. Ghani et. al

Azra A Ghani1, Muhammad Shahzad2, Syed Munib3,  Zafar  Ahmad  Khan4, Rahmat ali khan

Associate prof department of urology institute of kidney disease Peshawar

Assistant Prof department of urology MTI, LRH Peshawar

Prof of Nephrology IKD Peshawar

Assistant Prof Urologist MMC Mardan

Assistant Prof department of Nephrology  Miangul Abdul Haq Jahanzeb Kidney Hospital swat

Corresponding Author:  Muhammad Shahzad

Email: shahzadtauni@hotmail.com