The Relationship between Neutrophil to Lymphocyte Ratio and Osteoporosis

Abstract

Introduction: Osteoporosis is a chronic disease which commonly occurs in people after the age of 70 and it is important to identify the contributing factors. Therefore, this study aims to examine the relationship between neutrophil to lymphocyte ratio and osteoporosis.

Materials and methods: This study was conducted on 71 people (59.2%) with osteoporosis and 29 people (40.8%) without osteoporosis. Informed consent was obtained from the subjects and demographic data was recorded; neutrophil to lymphocyte ratio was also recorded. Chi square and Mann–Whitney U test were used to compare the data.

Findings: The findings of the study revealed that the average age of subjects with osteoporosis was significantly higher and the average height and weight of subjects with osteoporosis was significantly lower than subjects without osteoporosis. No statistically significant difference was found between the two groups of study in terms of the mean neutrophil to lymphocyte ratio (NLR). NLR was not associated with spinal or femoral Osteoporosis severity either.

Conclusion: As there is no association between NLR and osteoporosis and the related severity, it seems that NLR has no effect on Pathophysiology of osteoporosis, though more studies are required to examine this relationship.