Mucormycosis-Induced Maxillary Necrosis and Diabetes from NTH And HMC Hospitals in Peshawar

Abstract

Necrosis of the maxilla is quite unusual owing to the high vascularity of this tooth. For example, maxillary necrosis may be caused by herpes zoster, osteomyelitis, or fungal diseases such mucormycosis and aspergillosis. As an opportunistic, life-threatening fungal illness, mucormycosis mostly affects immunocompromised individuals. Inhalation of fungus spores causes infection of the nose and paranasal sinuses. Orbital and intracranial tissues may be infected directly or via blood arteries, depending on how quickly the infection spreads. Hard and soft tissue necrosis results from thrombosis caused by fungal invasion of arteries. An uncontrolled diabetic patient had maxillary necrosis due to mucormycosis, and we provide this case to highlight the need of early detection of this potentially deadly fungal infection.

We briefly address several illnesses that might cause maxillary necrosis and review current thinking in the therapy of mucormycosis. This fatal fungal infection may be reduced in mortality and morbidity by early identification and immediate treatment.